劉超紅，華中科技大學附屬同濟醫院過敏與臨床免疫研究所副所長，同濟兒童醫院兒研所副所長，88858cc永利官网微生物系教授，科研副主任，2017年國家自然科學基金優秀青年基金獲得者。2003年于武漢大學獲理學學士學位，2006年于中科院武漢病毒所獲碩士學位。2013于美國馬裡蘭大學帕克分校獲博士學位。2013以研究助理加入到聖裘德兒童研究醫院遲洪波實驗室。現在主要研究領域是呼吸和血液系統免疫相關疾病。研究方向包括兒童免疫缺陷性肺炎和自身免疫疾病的免疫異常機制，呼吸道病毒感染所導緻的宿主免疫系統紊亂以及哮喘産生的機制。以通訊作者發表43篇SCI論文。其工作在Immunity、 Blood、Journal of Allergy and Clinical Immunology、Nature Communications、Science Advances、PLos Biology、 Leukemia、 Journal of Experimental Medicine、 Cell report 和Journal of Immunology等雜志發表。任中國生理學會血液分會委員，亞太醫學生物免疫學會基礎免疫學分會副秘書長，湖北省生物免疫學會轉化醫學專委會副主委，Journal of Clinical and Translational Hepatology 雜志Associate editor和Journal of Leukocyte Biology編輯。擔任Signal Transduction and Targeted Therapy、Cellular and Molecular Immunology和eLife等雜志審稿人。以負責人身份承擔了國家重點研發計劃和國際合作項目等7項國家級項目,參與3項重點研發計劃。以第一完成人獲湖北省自然科學獎二等獎，培養了數名博士後和研究生。

聯系方式：chaohongliu80@126.com

發表文章

(^#Co-first author ,*Co-corresponding author)

Jiang P, Jing Y, Zhao S, Lan C, Yang L, Dai X, Luo L, Cai S, Zhu Y, Miller H, Lai J, Zhang X, Zhao X, Wu Y, Yang J, Zhang W, Guan F, Zhong B, Umehara H, Lei J, Dong L*,Liu C*.Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease. Nat Commun. 2024 Mar 23;15(1):2627. doi: 10.1038/s41467-024-45977-7. PMID: 38521787; PMCID: PMC10960850.IF=16.6

Yu H, Yang L, Han Z, Zhou X, Zhang Z, Sun T, Zheng F, Yang J, Guan F, Xie J,Liu C. SARS-CoV-2 nucleocapsid protein enhances the level of mitochondrial reactive oxygen species. J Med Virol. 2023 Dec;95(12):e29270. doi: 10.1002/jmv.29270. PMID: 38047459.IF=12.7

Yang Y, Miller H, Byazrova MG, Cndotti F, Benlagha K, Camara NOS, Shi J, Forsman H, Lee P, Yang L, Filatov A*, Zhai Z*,Liu C*. The characterization of CD8+ T-cell responses in COVID-19. Emerg Microbes Infect. 2024 Dec;13(1):2287118. doi: 10.1080/22221751.2023.2287118. Epub 2024 Jan 11. PMID: 37990907; PMCID: PMC10786432.IF=13.2

Gu H, Fu Y, Yu B, Luo L, Kang D, Xie M, Jing Y, Chen Q, Zhang X, Lai J, Guan F, Forsman H, Shi J, Yang L, Lei J, Du X, Zhang X*,Liu C*. Ultra-high static magnetic fields cause immunosuppression through disrupting B-cell peripheral differentiation and negatively regulating BCR signaling. MedComm (2020). 2023 Oct 1;4(5):e379. doi: 10.1002/mco2.379. PMID: 37789963; PMCID: PMC10542999.IF=10.1

Wang X, Guan F, Miller H, Byazrova MG, Cndotti F, Benlagha K, Camara NOS, Lei J, Filatov A*,Liu C*. The role of dendritic cells in COVID-19 infection. Emerg Microbes Infect. 2023 Dec;12(1):2195019. doi: 10.1080/22221751.2023.2195019. PMID: 36946172; PMCID: PMC10171120.IF=13.2

Yu H, Guan F, Miller H, Lei J,Liu C. The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development. Emerg Microbes Infect. 2022 Dec 30:2164219.IF=13.2

Du Z, Huang L, Dai X, Yang D, Niu L, Miller H, Ruan C, Li H, Hu L, Zhou L, Jian D, Sun J, Shi X, Huang P, Chen Y, Zhao X*,Liu C*. Progranulin regulates the development and function of NKT2 cells through EZH2 and PLZF. Cell Death Differ. 2022 Oct;29(10):1901-1912.IF=12.074

Zhu Y^#, Gu H^#, Yang L, Li N, Chen Q, Kang D, Lin S, Jing Y, Jiang P, Chen Q, Luo L, Liu J, Chang J, Li Z, Wang Y, Dai X, Miller H, Westerberg LS, Park CS, Kubo M, Gong Q, Dong L*,Liu C*. Involvement of MST1/mTORC1/STAT1 activity in the regulation of B-cell receptor signalling by chemokine receptor 2.Clin Transl Med. 2022 Jul;12(7):e887.IF=10.6

Dai Z^#, Mu W^#, Zhao Y, Cheng J, Lin H, Ouyang K, Jia X, Liu J, Wei Q, Wang M,Liu C, Tan T, Zhou J. T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape. Signal Transduct Target Ther. 2022 Mar 25;7(1):85.IF=38.120

He M, Saeed MB, Record J, Keszei M, Gonçalves Pinho L, Vasconcelos-Fontes L, D'Aulerio R, Vieira R, Oliveira MMS, Geyer C, Bohaumilitzky L, Thiemann M, Deordieva E, Buedts L, Matias Lopes JP, Pershin D, Hammarström L, Xia Y, Zhao X, Cunningham-Rundles C, Thrasher AJ, Burns SO, Cotta-de-Almeida V,Liu C, Shcherbina A, Vandenberghe P, Westerberg LS. Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation. J Allergy Clin Immunol. 2022 Mar;149(3):1069-1084.IF=14.291、

Jing Y^#, Luo L^#, Chen Y, Westerberg LS, Zhou P, Xu Z, Herrada AA, Park CS, Kubo M, Mei H, Hu Y, Lee PP, Zheng B, Sui Z, Xiao W, Gong Q, Lu Z*,Liu C*.SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism. Signal Transduct Target Ther. 2021 Sep 22;6(1):345.IF=38.120

Yang L, Li N, Yang D, Chen A, Tang J, Jing Y, Kang D, Jiang P, Dai X, Luo L, Chen Q, Chang J, Liu J, Gu H, Huang Y, Chen Q, Li Z, Zhu Y, Miller H, Chen Y, Qiu L, Mei H, Hu Y, Gong Q,Liu C*. CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation. Cell Death and Differentiation.2021 Sep;28(9):2616-2633.IF=10.717

He M*, Saeed MB, Record J, Keszei M, Gonçalves Pinho L, Vasconcelos-Fontes L, D'Aulerio R, Vieira R, Oliveira MMS, Geyer C, Bohaumilitzky L, Thiemann M, Deordieva E, Buedts L, Matias Lopes JP, Pershin D, Hammarström L, Xia Y, Zhao X, Cunningham-Rundles C, Thrasher AJ, Burns SO, Cotta-de-Almeida V,Liu C, Shcherbina A, Vandenberghe P, Westerberg LS*.Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.

J Allergy Clin Immunol. 2021 Aug 9:S0091-6749(21)01207-0. doi: 10.1016/j.jaci.2021.07.033. Online ahead of print.IF=10.793

Herrada AA*, Olate-Briones A, Rojas A,Liu C, Escobedo N, Piesche M*.Adipose tissue macrophages as a therapeutic target in obesity-associated diseases.Obes Rev. 2021 Jun;22(6):e13200.IF=9.213

Wang ZZ, Song J, Wang H, Li JX, Xiao Q, Yu Z, Wang ZC, Liu JX, Pan L, Yao Y, Chen CL, Lu X,Liu C, Gao P, Liu Z*. Stromal cells and B cells orchestrate ectopic lymphoid tissue formation in nasal polyps. Allergy. 2021 May;76(5):1416-1431.IF=13.146

Du Z^#, Chen A^#, Huang L, Dai X, Chen Q, Yang D, Li L, Miller H, Westerberg L, Ding Y, Tang X, Kubo M, Jiang L, Zhao X*, Wang H*,Liu C*. STAT3 couples with 14-3-3σ to regulate BCR signaling, B-cell differentiation, and IgE production. J Allergy Clin Immunol. 2021 May;147(5):1907-1923.e6.IF=10.228

Wang L^#, Jiang P^#, Zhao S, Liu H, Liu L, Mor G,Liu C*, Liao A*. The dynamic profile and potential function of B-cell subsets during pregnancy. Cell Mol Immunol. 2021 Apr;18(4):1082-1084.IF=22.096

Raynor JL,Liu C, Dhungana Y, Guy C, Chapman NM, Shi H, Neale G, Sesaki H, Chi H*.Hippo/Mst Signaling Coordinates Cellular Quiescence with Terminal Maturation in iNKT Cell Development and Fate Decisions. J Exp Med. 2020 Jun 1;217(6): e20191157.IF=11.743

Jing Y^#, Dai X^#, Yang L^#, Kang D, Jiang P, Li N, Cheng J, Li J, Miller H, Ren B, Gong Q, Yin W, Liu Z, Mattila P, Ning Q, Sun J, Yu B* andLiu C*.STING couples with PI3K to regulate actin reorganization during BCR activation. Science Advances. 2020 Apr 22; 6(17): eaax9455.*Co-corresponding author. IF=13.116

Jing Y^#, Kang D^#, Liu L, Huang H, Chen A, Yang L, Jiang P, Li N, Miller H,Liu Z, Zhu X, Yang J, Wang X, Sun J*,Liu Z*, Liu W*, Zhou X*,Liu C*.Dock2 couples with LEF-1 to regulate the expression of CD21 and B cell differentiation.Journal of Allergy and Clinical Immunology.2019 Nov; 144(5): p. 1377-1390 e4.*Co-corresponding author.IF=14.11

Xu C, Fang Y, Yang Z, Jing Y, Zhang Y,Liu C*,Liu W*.MARCKS Regulates Tonic and Chronic Active B Cell Receptor Signaling.Leukemia.2019 Mar;33(3):710-729.*Co-corresponding author.IF=9.944

Shi H,Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W*, Chi H*. Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R–STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. Immunity. 2018 Nov 20; 49 (5): 899-914.e6.IF=19.734

Huang L, Zhang Y, Xu C, Gu X, Niu L, Wang J, Sun X, Bai X, Xuan X, Li Q, Shi C, Yu B, Miller H, Yang G, Westerberg LS, Liu W, Song W, Zhao X*,Liu C*.Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. PLos Biology. 2017 Aug 18; 15(8): e2001750.*Co-corresponding author. IF=9.797

Bai X, Zhang Y, Huang L, Wang J, Li W, Niu L, Jiang H, Dai R, Zhou L, Zhang Z, Miller H, Song W, Zhao X,Liu C*.The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 down regulation. Blood.2016 Sep 29; 128(13):1723-34.IF=11.847

Zhang X^#, Dai R^#, Li W, Zhao H, Zhang Y, Zhou L, Du H, Luo G, Wu J, Niu L, An Y, Zhang Z, Ding Y, Song W,Liu C, Zhao X*.Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome. Blood.2016 Jun 23; 127(25):3180-91.IF=11.847

Song W*,Liu C, Seeley-Fallen MK, Miller H, Ketchum C, Upadhyaya A. Actin-mediated feedback loops in B-cell receptor signaling. Immunological Reviews. 2013 Nov; 256(1):177-89.IF=12.909

Liu C, Bai X, Wu J, Sharma S, Upadhyaya A,Dahlberg C, Westerberg L,Snapper S, Zhao X, Song W*.N-WASP is Essential for the Negative Regulation of B cell Receptor Signaling. Plos Biology. 2013 Nov; 11(11): e1001704.IF=11.771

Becker-Herman S^#, Meyer-Bahlburg A^#, Schwartz M^#, Jackson S, Hudkins K,Liu C, Sather B, Khim S, Liggitt D, Song W, Silverman G, Alpers C, Rawlings D*. WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.Journal of Experimental Medicine. 2011 Sep 26; 208(10):2033-42.IF=11.743

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主要著作
“B cell receptor signaling”, Methods in Molecular Biology, Springer， 2017
“Tcell receptor signaling”, Methods in Molecular Biology, Springer， 2020
“Invariant Natural Killer T cells”, Methods in Molecular Biology, Springer， 2021

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