
賀 軍
Email:junhe@mails.tjmu.edu.cn
個人簡介:博士,華中科技大學同濟醫學院88858cc永利官网教授,博士研究生導師,組胚學系黨支部書記,湖北省解剖學會理事。1994年畢業于泸州醫學院臨床醫療系,獲學士學位;2002年獲四川大學生理學專業碩士學位;2005年獲華中科技大學生命科學與技術學院生物醫學工程博士學位,同年入職同濟醫學院組織學與胚胎學系。研究方向:胰島β細胞分泌調控機制研究;CRAC通道生理病理功能及調控機制研究。近年來,在J Biol Chem,Cell Death Dis,J Colloid Interface Sci等雜志發表SCI收錄論文10餘篇。主持2項國家自然科學基金,1項教育部博士點基金,1項湖北省自然科學基金課題及2項校創新自主基金項目,并參與多項國家自然科學基金資助項目的研究工作。
發表論文:
· Huang C*, Shen X, Liu X, Chen Z, Shu B, Wan L, Liu H, He J*. Hybrid breath figure method: A new insight in Petri dishes for cell culture. J Colloid Interface Sci. 2019 Jan 17;541:114-122. doi: 10.1016/j.jcis.2019.01.074. (Corresponding author)(IF=7.489)
· Zhu ZD, Yu T, Liu HJ, Jin J, He J*. SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation. Cell Death Dis. 2018 Jan 19;9(2):50. doi: 10.1038/s41419-017-0073-9. ( Corresponding author)(IF=6.304)
· Yu T, Chen SB, Pan JY, Su CL, He J*. Optical investigations reveal the effects of 2-aminoethyldiphenyl borate on STIM1 puncta formation. J Innov Opt Heal Sci. 2018;11: 1850003(14 pages) DOI: 10.1142/S1793545818500037.( Corresponding author) (IF=1.661)
· Pan JY, Yuan S, Yu T, Su CL, Liu XL, He J*, Li H*. Regulation of L-type Ca2+ Channel activity and insulin secretion by Huntingtin-associated protein 1. J Biol Chem. 2016;291:26352-26363 ( Corresponding author) (IF=4.238)
· Jun He*, Tao Yu, Jing Ying Pan, He Li*. Visualisation and identification of the interaction between STIM1s in resting cells. PLoS ONE 2012; 7(3): e33377. doi:10.1371/journal.pone.0033377( Corresponding author)(IF=2.74)
· Shun Liu, Jun He, Honglin Jin, Fei Yang, Jinling Lu, Jie Yang. Enhanced dynamic range in a genetically encoded Ca2+ sensor. Biochem Bioph Res Co 2011; 412:155-159 (Co-first author) (IF=2.985)
· Liu H, Wang S, Hang W, Gao J, Zhang W, Cheng Z, Yang C, He J, Zhou J, Chen J, Shi A*. LET-413/Erbin acts as a RAB-5 effector to promote RAB-10 activation during endocytic recycling. J Cell Biol. 2018 Jan 2;217(1):299-314.
· Huang J, Zhou C, He J, Hu Z, Guan WC, Liu SH. Protective effect of reduced glutathione C60 derivative against hydrogen peroxide-induced apoptosis in HEK 293T cells. J Huazhong Univ Sci Technolog Med Sci. 2016;36:356-63.
· Wang Z, Peng T, Wu H, He J, Li H. HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells. Histochem Cell Biol. 2015;144:39-48.
· Shan-Shan Huang, Jun He, Dong-Ming Zhao, Xiao-Yuan Xu, Hui-Ping Tan, He Li. Effects of mutant Huntingtin on mGluR5-mediated dual signaling pathways: implications for therapeutic interventions. Cell Mol Neurobiol 2010; 30:1107–1115
· Austin Cape, Xingxing Chen, Chuan-En Wang, Ashley O’Neill, Yung-Feng Lin, Jun He, Xing-Shun Xu, Hong Yi, He Li, Shihua Li, Xiao-Jiang Li. Loss of Huntingtin-associated protein 1 impairs insulin secretion from pancreatic β−cells. Cell Mol Life Sci. 2012;69(8):1305-17
科研項目:
1. 國家自然科學基金面上項目:STIM1對胰島β細胞分泌活動的調控作用及機制研究(31371217),項目負責人;
2. 國家自然科學基金面上項目:亨廷頓蛋白相關蛋白1對内分泌細胞分泌活動的調控作用及機制研究(30871311),項目負責人;
3. 教育部博士點基金項目:亨廷頓蛋白相關蛋白1與囊泡分泌、轉運關系研究(20070487184),項目負責人;
4. 華中科技大學校創新自主基金項目:新型基因鈣探針的構建及其對神經元網絡活動監控的應用(2011JC024),項目負責人;
5. 湖北省自然科學基金項目:BDNF對海馬神經元鈣信号調控作用研究(16510012),2006.1-2007.12,項目負責人;
6. 華中科技大學校創新自主基金項目:P物質及其受體NK1-R在急性胰腺炎發病中的機制研究,項目負責人。