
徐旭林,博士,副教授。2004、2009年分别獲華中科技大學碩士、博士學位,2007年至2009年在美國弗吉尼亞州立大學做訪問學者。現主要從事藥理學教學和科研。
主要研究方向:精神神經藥理
主持的科研項目:
1.國家自然科學基金:
kcnq2 磷酸化水平調控海馬神經元m(kv7)通道活動依賴性轉運
代表性論文:
1. xu x, jiang m, wang y, smith t, baumgarten cm, wood ma, tseng gn.long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.plos one. 2010 apr 13;5(4):e10140.
3. jiang m, xu x, wang y, toyoda f, liu xs, zhang m, robinson rb, tseng gn.. dynamic partnership between kcnq1 and kcne1 and influence on cardiac iks current amplitude by kcne2. j biol chem. 2009 ;284(24):16452-62.
2. xu x, recanatini m, roberti m, tseng gn. probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (ns1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1h-isoindol-5-ylamino]-nicotinic acid (pd307243). mol. pharmacol. 2008 jun; 73(6):1709-21.
4. xu x, jiang m, hsu kl, zhang m, tseng gn. kcnq1 and kcne1 in the iks channel complex make state-dependent contacts in their extracellular domains. j gen physiol. 2008 jun; 131(6):589-603.