肖軍花

e-mail：sosxiao@163.com

個人簡介：副教授，碩士導師。2002、2005年分别獲華中科技大學碩士、博士學位，2007年至2009年留美做博士後，2012年1月至3月美國加州大學洛杉矶分校訪問學者。現主要從事藥理學教學和科研。

研究方向：肺纖維化發病機制及藥物幹預；哮喘氣道平滑肌高反應性和重構機制及藥物幹預；心律失常發病機制及藥物幹預等。

專著： jun-hua xiao, yong-xiao wang, yun-min zheng. calcium signaling in airway smooth muscle cells (transient receptor potential and orai channels in airway smooth muscle cells), pp35-48, 2014, springer international publishing, doi: 10.1007/978-3-319-01312-1_3, print isbn: 978-3-319-01311-4, online isbn: 978-3-319-01312-1.

代表性論文：

1 wang y, chen ms, liu hc, xiao jh, wang jl. the relationship between frequency dependence of action potential duration and the expression of trpc3 in rabbit ventricular myocardium. cell physiol biochem, 33:646-656, 2014. (通訊作者)

2 chen ms, xiao jh*, wang y, xu bm, gao l, wang jl. upregulation of trpc1 contributes to contractile function in isoproterenol-induced hypertrophic myocardium of rat. cell physiol biochem, 32(4):951-9, 2013. （通訊作者）

3 niu ch, wang y, liu jd, wang jl, xiao jh*. protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. eur j pharmacol, 714(1-3):112-9, 2013. （通訊作者）

4 zheng ym, park sw, stokes l, tang q, xiao jh, wang yx*. distinct activity of bk channel β1-subunit in cerebral and pulmonary artery smooth muscle cells. am j physiol cell physiol, 304(8):c780-9, 2013.

5 xiao jh, zheng ym, liao b, wang yx. functional role of canonical transient receptor potential 1 and canonical transient receptor potential 3 in normal and asthmatic airway smooth muscle cells. am j respir cell mol biol. 2010 jul;43(1):17-25.

6 xiao jh, zhang yl, feng xl, wang jl, qian jq. effects of isoliensinine on angiotensin ii-induced proliferation of porcine coronary arterial smooth muscle cells. j asian nat prod res. 2006 apr-may; 8(3):209-16.

7 xiao jh, zhang jh, chen hl, feng xl, wang jl. inhibitory effects of isoliensinine on bleomycin-induced pulmonary fibrosis in mice. planta med. 2005 mar; 71(3):225-30.

8 chang mj, xiao jh, wang y, yan yl, yang j, wang jl. 2, 3, 5, 4'-tetrahydroxystilbene-2-o-beta-d-glucoside improves gastrointestinal motility disorders in stz-induced diabetic mice. plos one, 7(12), e50291, 2012

9 zeng c, xiao jh, chang mj, wang jl*. beneficial effects of thsg on acetic acid-induced experimental colitis: involvement of upregulation of ppar-γ and inhibition of the nf-κb inflammatory pathway. molecules, 16, 8552-8568, 2011

10 wan j, zhao l, xu c, zhang s, zhang z, zeng c, chang m, xiao j, wang j*. effects of neferine on the pharmacokinetics of amiodarone in rats. biomed chromatogr, 25, 858–866 2011

11 鄧佳慧, 肖軍花*, 王嘉陵. 成年小鼠肺成纖維細胞分離純化及原代培養. 基礎醫學與臨床, 第32卷, 第6期, 713-714, 2012 (通訊作者)

承擔的主要科研項目：

國家自然科學基金：調節性t細胞與博萊黴素誘導肺纖維化發病病程及其藥物治療效果的相關性研究

回國留學人員啟動基金

華中科技大學創新基金

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