病理生理學系
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劉平

作者: 時間:2019-01-01 點擊量:



劉平,華中科技大學88858cc永利官网研究員、博士生導師。入選湖北省“百人計劃”。現任Frontiers in Molecular Neuroscience編委。擔任湖北省生物物理學會理事、湖北省病理生理學會理事、武漢病理生理學會理事。主持國家自然基金面上項目、華中科技大學“交叉研究支持計劃”。2008年在華中科技大學生命科學與技術學院生化與分子生物學專業取得博士學位。2008年-2014年在美國康涅狄格大學醫學院(University of Connecticut Health)神經生物學系做博士後研究。2014年-2018年在該系擔任研究助理。2019年任康涅狄格大學醫學院講師。2019年9月入職華中科技大學88858cc永利官网,病理生理學系。

聯系郵箱:pingl@hust.edu.cn


研究方向

主要以秀麗線蟲(C. elegans)和小鼠為模式動物研究:

1.動物行為、學習與記憶的神經環路和突觸機制。

2.神經-免疫互作。


發表論文

#Co-first author*Corresponding author

1.Zhan, X., Chen, C., Niu, L., Du, X., Lei, Y., Dan, R., Wang, Z.-W., andLiu, P.*(2023). Locomotion modulates olfactory learning through proprioception in C. elegans. Nature Communications 14, 4534. 10.1038/s41467-023-40286-x.

2.Mueller, B.D., Merrill, S.A., Watanabe, S.,Liu, P., Niu, L.-G., Singh, A., Maldonado-Catala, P., Cherry, A., Rich, M.S., Silva, M., et al. (2023). CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles. eLife 12, e81407. 10.7554/eLife.81407.

3.Li, X., Chen, C., Zhan, X., Li, B., Zhang, Z., Li, S., Xie, Y., Song, X., Shen, Y., Liu, J.,Liu, P*, Liu, G*, Yang, X*. (2021). R13 preserves motor performance in SOD1G93A mice by improving mitochondrial function. Theranostics 11, 7294-7307. 10.7150/thno.56070.

4.Shui, Y.,Liu, P., Zhan, H., Chen, B., and Wang, Z.W. (2020). Molecular basis of junctional current rectification at an electrical synapse. Sci Adv 6, eabb3076. 10.1126/sciadv.abb3076.

5.Niu, L.G.,Liu, P., Wang, Z.W., and Chen, B.J. (2020). Slo2 potassium channel function depends on RNA editing-regulated expression of a SCYL1 protein. Elife 9. ARTN e5398610.7754/eLife.53986.

6.Niu, L.G., Li, Y., Zong, P.Y.,Liu, P., Shui, Y., Chen, B.J., and Wang, Z.W. (2020). Melatonin promotes sleep by activating the BK channel in C. elegans. P Natl Acad Sci USA 117, 25128-25137. 10.1073/pnas.2010928117.

7.Liu, P.#, Chen, B., and Wang, Z.W. (2020). GABAergic motor neurons bias locomotor decision-making in C. elegans. Nature Communications 11, 5076. 10.1038/s41467-020-18893-9.

8.Liu, P.#, Wang, S.J., Wang, Z.W., and Chen, B.J. (2018). HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans. Journal of Neuroscience 38, 1073-1084. 10.1523/Jneurosci.1991-17.2017.

9.Hawk, J.D., Calvo, A.C.,Liu, P., Almoril-Porras, A., Aljobeh, A., Torruella-Suarez, M.L., Ren, I., Cook, N., Greenwood, J., Luo, L., et al. (2018). Integration of Plasticity Mechanisms within a Single Sensory Neuron of C. elegans Actuates a Memory. Neuron 97, 356-367 e354. 10.1016/j.neuron.2017.12.027.

10.Niu, L.G.,Liu, P., Shui, Y., Mailler, R., Wang, Z.W., and Chen, B. (2017). BKIP-1, an auxiliary subunit critical to SLO-1 function, inhibits SLO-2 potassium channel in vivo. Sci Rep 7, 17843. 10.1038/s41598-017-18052-z.

11.Liu, P.#, Chen, B., Mailler, R., and Wang, Z.W. (2017). Antidromic-rectifying gap junctions amplify chemical transmission at functionally mixed electrical-chemical synapses. Nature Communications 8, 14818. 10.1038/ncomms14818.

12.Chen, B.,Liu, P., Hujber, E.J., Li, Y., Jorgensen, E.M., and Wang, Z.W. (2017). AIP limits neurotransmitter release by inhibiting calcium bursts from the ryanodine receptor. Nature Communications 8, 1380. 10.1038/s41467-017-01704-z.

13.Boisvert, E.M., Engle, S.J., Hallowell, S.E.,Liu, P., Wang, Z.W., and Li, X.J. (2015). The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. Sci Rep 5, 16821. 10.1038/srep16821.

14.Liu, P.#, Chen, B., and Wang, Z.W. (2014). SLO-2 potassium channel is an important regulator of neurotransmitter release in Caenorhabditis elegans. Nature Communications 5, 5155. 10.1038/ncomms6155.

15.Liu, P.#, Chen, B., and Wang, Z.W. (2013). Postsynaptic current bursts instruct action potential firing at a graded synapse. Nature Communications 4, 1911. 10.1038/ncomms2925.

16.Liu, P.#, Chen, B., Altun, Z.F., Gross, M.J., Shan, A., Schuman, B., Hall, D.H., and Wang, Z.W. (2013). Six innexins contribute to electrical coupling of C. elegans body-wall muscle. PLoS One 8, e76877. 10.1371/journal.pone.0076877.

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