劉恭平，男，博士，教授，博士生導師。華中科技大學學術新人獎，教育部“新世紀優秀人才”計劃獲得者。1997年畢業于同濟醫科大學（現華中科技大學同濟醫學院），獲醫學學士學位；2000年獲華中科技大學同濟醫學院醫學碩士學位；2005年獲華中科技大學同濟醫學院醫學博士學位（勞動衛生與環境衛生學）；2005年9月進入華中科技大學同濟醫學院基礎學部病理生理系做博士後，師從王建枝教授，從事ad發病機制的研究。2007年12月博士後出站，2008年1月留校擔任教學和科研工作。

研究方向:

神經退行性疾病的發病機制、早期診斷及治療策略

發表的有關論文（第一作者或通訊作者）：

1.jiang x, chai gs, wang zh, hu y, li xg, ma zw, wang q, wang jz, liu gp.camkii-dependent dendrite ramification and spine generation promote spatialtraining-induced memory improvement in a rat model of sporadic alzheimer'sdisease. neurobiol aging. 2014 oct 16. pii: s0197-4580(14)00675-7.

2.shang xl, wang qb, liu xp, yao xq, cao fy, wang q, zhang jy, wang jz, liu gp. fluorocitrate induced the alterations of memory-related proteins and tauhyperphosphorylation in sd rats. neurosci lett. 2014 oct 28;584c:230-235.

3.zhang y, ma rh, li xc, zhang jy, shi hr, wei w, luo dj, wang q, wang jz, liup. silencing [formula: see text] rescues tau pathologies and memory deficitsthrough rescuing pp2a and inhibiting gsk-3β signaling in human tau transgenicmice. front aging neurosci. 2014 jun 17;6:123.

4.luo dj, feng q, wang zh, sun ds, wang q, wang jz, liu gp. knockdown ofphosphotyrosyl phosphatase activator induces apoptosis via mitochondrial pathway and the attenuation by simultaneous tau hyperphosphorylation. j neurochem. 2014sep;130(6):816-25.

5.duan dx, chai gs, ni zf, hu y, luo y, cheng xs, chen nn, wang jz, liu gp.phosphorylation of tau by death-associated protein kinase 1 antagonizes thekinase-induced cell apoptosis. j alzheimers dis. 2013;37(4):795-808.

6.liu gp, wei w, zhou x, shi hr, liu xh, chai gs, yao xq, zhang jy, peng cx, hu j, li xc, wang q, wang jz. silencing pp2a inhibitor by lenti-shrna interferenceameliorates neuropathologies and memory deficits in tg2576 mice. mol ther. 2013dec;21(12):2247-57.

7.luo y, nie yj, shi hr, ni zf, wang q, wang jz, liu gp. ptpa activates protein phosphatase-2a through reducing its phosphorylation at tyrosine-307 withupregulation of protein tyrosine phosphatase 1b. biochim biophys acta. 2013may;1833(5):1235-43.

8.chai gs, jiang x, ni zf, ma zw, xie aj, cheng xs, wang q, wang jz, liu gp.betaine attenuates alzheimer-like pathological changes and memory deficitsinduced by homocysteine. j neurochem. 2013 feb;124(3):388-96.

9.yao xq, li xc, zhang xx, yin yy, liu b, luo dj, wang q, wang jz, liu gp.glycogen synthase kinase-3β regulates leucine-309 demethylation of proteinphosphatase-2a via ppmt1 and pme-1. febs lett. 2012 jul 30;586(16):2522-8.

10.liu xp, zheng hy, qu m, zhang y, cao fy, wang q, ke d, liu gp, wang jz.upregulation of astrocytes protein phosphatase-2a stimulates astrocytes migrationvia inhibiting p38 mapk in tg2576 mice. glia. 2012 sep;60(9):1279-88.

11.chen nn, luo dj, yao xq, yu c, wang y, wang q, wang jz, liu gp. pesticidesinduce spatial memory deficits with synaptic impairments and an imbalanced tauphosphorylation in rats. j alzheimers dis. 2012;30(3):585-94.

12.wei w, liu yh, zhang ce, wang q, wei z, mousseau dd, wang jz, tian q, liu gp.folate/vitamin-b12 prevents chronic hyperhomocysteinemia-induced tauhyperphosphorylation and memory deficits in aged rats. j alzheimers dis.2011;27(3):639-50.

13.yao xq, zhang xx, yin yy, liu b, luo dj, liu d, chen nn, ni zf, wang x, wang q, wang jz, liu gp. glycogen synthase kinase-3β regulates tyr307 phosphorylation of protein phosphatase-2a via protein tyrosine phosphatase 1b but not src.biochem j. 2011 jul 15;437(2):335-44.

14.liu gp, wei w, zhou x, zhang y, shi hh, yin j, yao xq, peng cx, hu j, wang q,li hl, wang jz. i(2)(pp2a) regulates p53 and akt correlatively and leads theneurons to abort apoptosis. neurobiol aging. 2012 feb;33(2):254-64.

15.liu gp, zhang y, yao xq, zhang ce, wang q, wang jz. activation of glycogen       synthase kinase-3 inhibits protein phosphatase-2a and the underlying mechanisms. neurobiol aging. neurobiol aging. 2008 sep;29(9):1348-58

16.yao z, guo z, yang c, tian q, gong cx, liu g, wang jz. phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation. neuroscience. 2010 jun 30;168(2):405-15.

17.liu gp, shi n. the inhibitory effects of deltamethrin on dopamine biosynthesis inrat pc12 cells. toxicol lett. 2006;161(3):195-9.

18.liu gp, ma q,shi n. tyrosine hydroxylase as a target for deltamethrin in the nigrostriatal dopaminergic pathway. biomed environ sci. 2006;19:27-34.

主持基金：

2015年國際自然科學基金（面上）；

2013年國家自然科學基金（面上）；

2012年國際基金項目美國阿爾茨海默病協會的青年學者研究基金（第一）；

2009年國際基金項目美國阿爾茨海默病協會的研究者啟動研究基金（iirg-09-13343；第三）；

2008年國家自然科學基金青年基金（30801212，第一）；

2007年中國博士後科學基金 （二等資助，第一）；

國家自然科學基金（30700277，第三）；

863計劃（2006aa02z4a1，成員）

教育部創新團隊（成員）

2010年華中科技大學學術新人獎

2012年教育部新世紀創新人才計劃

所獲獎勵：

2008年中華醫學科技獎貳等獎排名第四

2008年 湖北省自然科學獎一等獎排名第三

2006年湖北省優秀博士論文獎